FLUZONE HIGH-DOSE QUADRIVALENT AND FLUBLOK QUADRIVALENT CAN HELP PREVENT FLU-RELATED HOSPITALIZATIONS1,2
Fluzone High-Dose Quadrivalent and Flublok Quadrivalent are the only higher-dose flu shots proven to prevent more flu in older adults than a standard-dose influenza vaccine in RCT.4,5
In a randomized, controlled efficacy trial, Fluzone High-Dose (Influenza Vaccine) trivalent formulation provided 24% (95% CI: 10-37) better protection against influenza due to any lab-confirmed circulating strains vs a standard-dose influenza vaccine in adults 65 years of age and older.1,5
The efficacy of the trivalent formulation is relevant to Fluzone High-Dose Quadrivalent since both vaccines are manufactured according to the same process and have overlapping compositions.1
Solicited systemic adverse reactions and solicited injection-site reactions were slightly more frequent with Fluzone High-Dose as compared to a standard-dose influenza vaccine.6CI=confidence interval.
In a randomized, controlled efficacy trial, Flublok Quadrivalent provided 30% (95% CI: 10-47) better protection against influenza due to any PCR-confirmed circulating strains vs a standard-dose quadrivalent inactivated influenza vaccine in adults 50 years of age and older.2,4
In adults 50 years of age and older, the most common (≥10%) injection-site reactions were tenderness (34%) and pain (19%); the most common (≥10%) solicited systemic adverse reactions were headache (13%) and fatigue (12%).2
aThe information above is available at CMS.gov. The information is provided for informational purposes only and is not a guarantee of coverage. The information is gathered from various resources and is subject to change.