FLUZONE HIGH-DOSE AND FLUBLOK ARE PROVEN TO PREVENT FLU AND SHOWN TO REDUCE ITS COMPLICATIONS
Fluzone High-Dose and Flublok are the only higher-dose flu shots proven to prevent more flu in older adults than a standard-dose influenza vaccine in RCTs.3,6,8
In a randomized controlled trial, Fluzone High-Dose (Influenza Vaccine) trivalent formulation provided 24% (95% CI: 10-37) better protection against influenza due to any lab-confirmed circulating strains vs a standard-dose influenza vaccine in adults 65 years of age and older.2,8
Solicited injection-site reactions and systemic adverse reactions were more frequent after vaccination with Fluzone High-Dose compared to Fluzone.2
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In a randomized controlled trial, Flublok (quadrivalent) provided 30% (95% CI: 10-47) better protection against influenza due to any PCR-confirmed circulating strains vs a standard-dose quadrivalent inactivated influenza vaccine in adults 50 years of age and older.1,3
For Flublok, in adults 18 through 64 years of age, the most common injection site adverse reaction was pain; the most common solicited systemic adverse reactions were headache, fatigue, and myalgia. In adults 65 years of age and older, the most common injection-site adverse reaction was pain; the most common solicited systemic adverse reactions were fatigue and headache.
The efficacy of the quadrivalent formulation is relevant to Flublok since both vaccines are manufactured according to the same process and have overlapping compositions.1
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PCR=polymerase chain reaction.aThe information above is available at CMS.gov. The information is provided for informational purposes only and is not a guarantee of coverage. The information is gathered from various resources and is subject to change.